Tombus virus defective interfering (DI) RNA region 3 | |
---|---|
Predicted secondary structure and sequence conservation of Tombus_3_III | |
Identifiers | |
Symbol | Tombus_3_III |
Rfam | RF00215 |
Other data | |
RNA type | Cis-reg |
Domain(s) | Viruses |
SO | 0000233 |
Tombus virus defective interfering (DI) RNA region 3 is an important cis-regulatory region identified in the 3' UTR of Tombusvirus defective interfering particles (DI).[1]
Defective interfering RNAs are small sub-viral replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for replication of the host virus.[1] This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating viral replication.[1]